Hyperuricemia in Dalmatian Dog (as in all breeds) is inherited, but unlike other races, the uricase gene "normal" is not present in the gene pool of the breed at all. So there is no possibility of eliminating hyperuricemia among pure Dalmatians. The only possible solution to this problem must be crossed Dalmatians with other breeds to reintroduce the uricase gene "normal". This led to the founding of the Dalmatian-Pointer backcross, which aims to re-enter the normal uricase gene into the Dalmatian breed. The English Pointer used a backcross progeny, only later Dalmatians were pure. This project started in 1973 by Dr. Robert Schaible. The first cross (F1) hybrids do not resemble Dalmatians very closely. The F1, then crossed back to pure blood. This culture produces most closely resembles the pure Dalmatian puppies. For the fifth generation in 1981, both looked like thoroughbreds, Dr. Schaible convinced the AKC to allow two of the hybrids to be registered as a breed. Then, President William F. AKC Stifel said: "If there is a logical and scientific to correct health problems associated with the genetic characteristics of certain breeds dog and preserve the integrity of the breed standard, which corresponds to the American Kennel Club to lead the way" . The Dalmatian Club of America's (DCA) board of directors supported this decision, however, quickly became very controversial among the club members. A vote by DCA members opposed the registration of hybrids, making the AKC to ban registration to any dog of children.
During the annual general meeting of the DCA in May 2006 the backcross issue was discussed again by club members. In June the same year DCA members were presented with the opportunity to vote on whether to reopen the debate Dalmatian backcross design. The results of this vote were nearly 2:1 in favor of reconsidering the project to support the DCA. This began with the publication of articles presenting more information both in support and questioned the need for this project. In July 2011, the AKC has agreed to allow the registration of Backcross Dalmatians.
In 2010, the United Kingdom Kennel Club registered a guy named Dalmatian backcrossed. Cab is in the first place. Several restrictions were imposed in the dog. Even if the dog is at least 13 generations of the original pointer cross, F1 to F3 progeny will be indicated on the registration certificate with an asterisk (which "indicates unclean livestock or unverified") has no children, how can export pedigree for the next five years, and everything must be tested for health. UK breed clubs oppose the decision of the Dalmatian Kennel Club.