Tuesday, January 8, 2013

Von Willebrand Disease in Dogs


What is Von Willebrand's disease?

Von Willebrand's which is borne diseases that reduce the ability of blood clots in dogs. The symptoms of von Willebrand disease in dogs is quite similar to the symptoms displayed by people who suffer from hemophilia A.

The best way to prevent von Willebrand's disease is to never let the dogs with von Willebrand's disease to breed. To accomplish this, all dogs should be tested for von Willebrand's disease before multiplying. Because this is borne diseases, it will be much less common if all breeders test their dogs.

Dog breed is highly prone to von Willebrand's disease


Von Willebrand's disease symptoms in dogs

Von Willebrand's is borne disease that often manifests when the puppy is still very young. A bleeding will cause suspicion and von Willebrand's disease is often diagnosed after spaying or neutering procedure. In dogs breeds where von Willebrand's disease is common, many veterinarians will perform screening tests before doing any operation planned in dogs of such breed.

In dogs with borderline von Willebrand's factor, vaccination may cause a slight decrease in platelet function. The same is true for treatment with non-steroidal anti-inflammatory drugs (NSAIDs called: s). If this happens, the symptoms are not normal bruising and / or bleeding. This sudden decrease in platelet function is temporary.

Von Willebrand's disease testing for dogs

Two different methods are used for von Willebrand's testing: von Willebrand's blood tests and von Willebrand's DNA test. A blood test is the classical method for detecting this disease in dogs, von Willebrand's factor, measured in blood samples from dogs and compared with results from other dogs. The result expressed in percentage, and thus may have for your dog to get the result of more than 100%, for example, 120% or 160%, if they have the von Willebrand's factor which is much higher than standard yield. If the result is up to 49%, a dog is a carrier of a genetic influence or von Willebrand's disease. If the result is 50-69%, the dog is the case bounds. Yield between 70% and 180% of all considered normal.

Von Willebrand's disease treatment for dogs

In situations where the dog will bleed, such as operations, it is possible to manage the von Willebrand's factor to dog through transfusion. Von Willebrand's factor may also be given to the dog to stop the bleeding accident. It is not possible for a veterinarian to obtain pure von Willebrand's factor, but they have access to blood products mentioned kriopresipitat very rich in von Willebrand's factor. A transfusion cryopresipitat will make a significant difference in the dog for about 4 hours after transplantation, respectively. In cases where the veterinarian has cryopresipitat not, the second best option is a complete plasma.

A hormone called desmopressin acetate (DDAVP) has been shown to cause a sudden release of von Willebrand factor in the blood stream of dogs and can therefore help to dog suffering from von Willebrand disease. When a dog is suffering from von Willebrand disease DDAVP injection of bleeding time will be reduced for about 2 hours after the onset of a period of 30 minutes in length.

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