Friday, January 11, 2013

Cryptococcosis Infection in Dogs


What is Cryptococcosis?

Cryptococcosis is a disease caused by the fungus Cryptococcus neoformans named. The disease is more common in cats, but dogs and humans do not get it sometimes. When dogs become infected with Cryptococcus neoformans in, can cause severe damage to spread to the central nervous system. Humans rarely get Cryptococcosis unless they have a compromised immune system, such as immune suppressing drugs taken after the transplant.

Cryptococcosis delivery for dogs

Cryptococcus neoformans is found worldwide and various environments. It is commonly found in soil and bird dirt, grime, especially pigeons, which makes extensive in places where wild or pet pigeons occur in large numbers. Transmission to dogs usually occurs through inhalation of spores, but spores can also enter through broken skin. When Cryptococcus neoformans occurs in bird shit, get the non-encapsulated form. This form is not greater than 1 ╬╝mand to get inhaled into the deeper parts of the lungs of dogs.

Cryptococcosis symptoms in dogs

Compared to cats, dogs are more prone to develop disseminated for disease. Cryptococcosis diseminata means that the mushrooms had spread from the initial point of entry to other parts of the body of a dog. Cryptococcus neoformans can affect the eyes and central nervous system (CNS) and cause optic neuritis, granulomatous chorioretinitis and meningoencephalitis. About 50 percent of dogs diagnosed to have lesions in their respiratory tract, which is often the lungs, and most dogs have a granuloma in more than one system. Lesions may develop in the nasal cavity. Cryptococcus neoformans is quite often attacks the kidneys, lymph nodes, spleen and liver of dogs, and general lack of almond, heart valves, thyroid, adrenal, muscle, pancreas, gastrointestinal tract, bone, myocardium, and prostate.

When Cryptococcosis cause lesions in dogs, they can be different from the kind of granuloma mass jelly made by many organisms (often with very little inflammation). Kriptokokosis lesions in dogs usually consists of an aggregate of encapsulated organisms covered by reticular connective tissue.

Cryptococcosis treatment for dogs

In most situations, the preferred medicine for dogs Cryptococcosis is Flukonazol or Itrakonazol. Flukonazol normal dosage for dogs suffering Cryptococcosis varies from 2 to 10 mg per kilogram of body weight Flukonazol per day. When Itraconazole is used, the standard dose of 10 mg per kilogram of body weight per day. Another possibility is flusitosin, but defensive medicine can grow if you just got a dog and most of flusitosin veterinarian for choosing to combine with Amfoterisin B.

Given subcutaneously Amfoterisin B Cryptococcosis is generally used for severe infections in dogs, usually 0.5 to 0.8 mg / kg diluted in saline containing 0.45% dextrose 2.5%. If a dog weighing up to 20 kg, 500 milliliters is enough. If a dog weighing more than 20 kg, 1,000 milliliters is the standard dose. Given subcutaneously Amfoterisin B is usually given 2-3 times a day for dogs suffering severe Cryptococcosis. Amfoterisin B lipid complex is another alternative here, the standard dosage for dogs with Cryptococcosis is 2-3 mg / kg, given three times a week. Treatment regimens should normally include at least 12-15 treatments, which lasted for at least 4 to 5 weeks.

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